Advancements in genomics, such as next-generation sequencing (NGS), CRISPR gene editing, and genome-wide association studies (GWAS), are significantly shaping personalized medicine. NGS enables comprehensive genomic profiling, allowing for the identification of genetic mutations and variations linked to diseases, which can inform tailored treatment plans. CRISPR technology allows for precise gene editing, offering potential cures for genetic disorders by directly modifying DNA. GWAS helps identify genetic factors influencing disease susceptibility, paving the way for targeted therapies. These advancements enable more personalized, effective treatments, optimize drug dosages, and improve prevention strategies based on an individual's genetic makeup, ultimately transforming the approach to healthcare.